Caffeine Side Effects

Although caffeine in moderate amounts poses no major health risks, the body quickly develops tolerance to the effects of caffeine, along with a mild physical and psychological dependency.

For example, tolerance to caffeine-related sleep disruption disappears in about a week among people who drink 3–4 cups of coffee daily. The amount of caffeine it takes to reach this state is highly variable.

Discontinuing caffeine among regular users causes withdrawal symptoms. These can include headaches (very common), irritability, nausea, fatigue, sleepiness, inability to concentrate, and mild depression. Caffeine withdrawal symptoms begin 12–24 hours after caffeine is stopped.

Withdrawal symptoms peak at around 48 hours, and can last up to five days. Tapering caffeine use, for example cutting down on caffeine by the equivalent of half a cup of coffee (about 50 mg) a day, minimizes or eliminates withdrawal symptoms.

People who use more than about 500 mg (the amount varies greatly among individuals) of caffeine a day may develop a condition called caffeinism. Caffeinism produces unpleasant sensations, some of which are similar to withdrawal symptoms.

Symptoms caffeine overuse include restlessness, irritability, nervousness, anxiety, muscle twitching, headaches, inability to fall asleep, and a racing heart.

Severe overuse of caffeine can cause four psychiatric disorders recognized by the American Psychiatric Association and described in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Caffeine is considered the cause of these disorders after other causes have been ruled out.

-Caffeine intoxication: Usually the result of taking caffeine pills (e.g., NoDoz), this condition causes mental changes, rambling thoughts and speech, irregular heart beat, and all symptoms associated with overuse. In severe cases death can result from ventricular fibrillation (unsynchronized contractions of the ventricle of the heart).

-Caffeine-induced anxiety disorder: Severe anxiety that interferes with daily social interactions and occurs after caffeine intoxication or heavy long-term use of caffeine.

-Caffeine-induced sleep disorder: An inability to sleep that is so great it requires medical/psychiatric attention and occurs after prolonged caffeine consumption.

-Non-specific caffeine-induced disorder: Disorders not listed that are attributable to either acute or long-term caffeine consumption.

Children get most of their caffeine from soft drinks. Parents should choose soft drinks that contain little or no caffeine or replace soft drinks with water, fruit juice, or low-fat milk.

Adolescents are increasingly using energy drinks and energy bars containing caffeine. At the same time, many adolescents start drinking coffee. Parents educate their children about the effects of caffeine and encourage them to monitor their caffeine consumption from all sources.

Accidental overdose from caffeine pills can be fatal. Caffeine tablets, like all drugs, should be kept out of reach of children. Children who accidentally eat caffeine pills need immediate medical attention from a physician or emergency room.