Causes of Electrolyte Imbalances

An electrolyte imbalance occurs when the concentration of a specific electrolyte is either too high or too low. The concentration of electrolytes is strongly affected by the amount of fluid in the body. Fluid balance is largely controlled by hormones that act on the kidneys and regulate how much urine the kidneys produce.

The average male adult loses about 1.5-2.5 L of water daily through urine production, sweating, breathing out water vapor, and bowel movements depending on exercise levels and environmental temperature. The United States Institute of Medicine recommends that adult men drink a minimumof 3 L of liquids a day, and that women drink a minimum of 2.2 L to replace lost water.

Dehydration is a major cause of electrolyte imbalance. It occurs whenever water is lost from the body and not replaced fairly quickly. When fluids are lost, electrolytes in those fluids are lost too, increasing the risk of electrolyte imbalance. Dehydration can be caused in many ways. These include:

-Heavy exercise, especially in hot weather. Sodium and water are both lost through the skin with heavy sweating.

-Limited fluid intake. This is a particular problem with the elderly, especially those who are unable to walk or are bedridden.

-Severe vomiting and diarrhea. Large amounts of water and many electrolytes that would normally be absorbed in the intestines are lost with diarrhea and vomiting. Small children with diarrhea can become seriously dehydrated in less than one day. Infants can become dehydrated within hours.

-High fever. Increased water loss through the skin due to fever is especially serious in infants and young children.

-Severe burns. More water is lost from the surface of the body when the skin is not there to prevent evaporation, and damaged cells release their electrolytes into interstitial fluid, upsetting the electrolyte balance.

Electrolyte imbalances can have other causes unrelated to dehydration. These include:

-Kidney damage or kidney failure. This is a common cause of electrolyte imbalances in the elderly and can be fatal.

-Anorexia nervosa (self starvation) or bulimia nervosa (binge and purge eating).

-Excessive intake of water. Called water intoxication, this can result in swelling in the brain. In 2007, a Sacramento, California, woman died when she participated in a radio station contest that involved drinking large amounts of water in a short period of time.

-Some drugs, herbal supplements, and chemotherapy. Some medications/treatments selectively increase the excretion of certain electrolytes, cause the body to retain excess water, or stimulate the kidneys to produce excess urine.

-Hormonal imbalances in the production of hormones that regulate the kidneys. This causes too little or too much urine to be produced.

-Cancer. Some tumors produce chemicals that upset electrolyte balance.

-Abuse of electrolyte supplements.